Function and Biology Details
Reaction catalysed:
Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Aminopeptidase N (preferred)
PDBe Complex ID:
PDB-CPX-537864 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Aminopeptidase N
Molecule details ›
Chains: A, B, C, D
Length: 945 amino acids
Theoretical weight: 107.29 KDa
Source organism: Sus scrofa
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Structure domains:
Length: 945 amino acids
Theoretical weight: 107.29 KDa
Source organism: Sus scrofa
Expression system: Cricetulus griseus
UniProt:
- Canonical:
P15145 (Residues: 36-963; Coverage: 96%)
Sequence domains:
Structure domains:
Ligands and Environments
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-2
Spacegroup:
P1
Expression system: Cricetulus griseus
