5le5

X-ray diffraction
1.8Å resolution

Native human 20S proteasome at 1.8 Angstrom

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 28-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127173 (preferred)
Entry contents:
14 distinct polypeptide molecules
Macromolecules (14 distinct):
Proteasome subunit alpha type-2 Chains: A, O
Molecule details ›
Chains: A, O
Length: 234 amino acids
Theoretical weight: 25.93 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P25787 (Residues: 1-234; Coverage: 100%)
Gene names: HC3, PSC3, PSMA2
Sequence domains:
Structure domains: Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Proteasome subunit alpha type-4 Chains: B, P
Molecule details ›
Chains: B, P
Length: 261 amino acids
Theoretical weight: 29.53 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P25789 (Residues: 1-261; Coverage: 100%)
Gene names: HC9, PSC9, PSMA4
Sequence domains:
Structure domains: Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Proteasome subunit alpha type-7 Chains: C, Q
Proteasome subunit alpha type-5 Chains: D, R
Proteasome subunit alpha type-1 Chains: E, S
Proteasome subunit alpha type-3 Chains: F, T
Proteasome subunit alpha type-6 Chains: G, U
Proteasome subunit beta type-7 Chains: H, V
Proteasome subunit beta type-3 Chains: I, W
Proteasome subunit beta type-2 Chains: J, X
Proteasome subunit beta type-5 Chains: K, Y
Proteasome subunit beta type-1 Chains: L, Z
Proteasome subunit beta type-4 Chains: M, a
Proteasome subunit beta type-6 Chains: N, b

Ligands and Environments

2 modified residues:

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup: P212121
Unit cell:
a: 113.44Å b: 202.77Å c: 316Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.212