› 5lfe

X-ray diffraction
2.3Å resolution

Protruding domain of GII.4 human norovirus isolate 8-14 in complex with HBGA type B (triglycan)

Released:
DOI: 10.2210/pdb5lfe/pdb
PDB entry 5lfe coloured by chain, front view.
PDB entry 5lfe coloured by chain, side view.
PDB entry 5lfe coloured by chain, top view.
Source organism: Norovirus Hu/GII.4/Sydney/NSW0514/2012/AU
Entry authors: Singh BK, Hansman GS

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-516996 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
VP1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 309 amino acids
Theoretical weight: 34.2 KDa
Source organism: Norovirus Hu/GII.4/Sydney/NSW0514/2012/AU
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: M4QNL3 (Residues: 206-511; Coverage: 59%)
Sequence domains: Calicivirus coat protein C-terminal
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GLA, FUC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P21
Unit cell:
a: 63.83Å b: 55.42Å c: 87.1Å
α: 90° β: 99.38° γ: 90°
R-values:
R R work R free
0.235 0.232 0.276
Expression system: Escherichia coli BL21(DE3)

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