› 5szp

X-ray diffraction
3.1Å resolution

Protocadherin Gamma B7 extracellular cadherin domains 1-4 P21 crystal form

Released:
DOI: 10.2210/pdb5szp/pdb
PDB entry 5szp coloured by chain, front view.
PDB entry 5szp coloured by chain, side view.
PDB entry 5szp coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
γ-Protocadherin structural diversity and functional implications.
Goodman KM, Rubinstein R, Thu CA, Mannepalli S, Bahna F, Ahlsén G, Rittenhouse C, Maniatis T, Honig B, Shapiro L
OpenAccess logo Elife 5 (2016)
PMID: 27782885

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-571509 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cadherin domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 423 amino acids
Theoretical weight: 47.3 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q91XX3 (Residues: 31-445; Coverage: 46%)
Gene name: Pcdhgb7
Sequence domains:
Structure domains: Cadherins

Ligands and Environments

4 bound ligands:
Ligand CA 18 x CA
Ligand MAN 7 x MAN
Ligand NAG 1 x NAG
Ligand TMO 1 x TMO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 83.813Å b: 45.549Å c: 127.072Å
α: 90° β: 96.91° γ: 90°
R-values:
R R work R free
0.259 0.256 0.31
Expression system: Homo sapiens

Quick links

Citations

12 review citations

Regulation of neural circuit formation by protocadherins.
Peek et al. (2017)
11 more

6 mentions without citation

Visualization of clustered protocadherin neuronal self-recognition complexes.
Brasch et al. (2019)
5 more