5ueq

X-ray diffraction
1.7Å resolution

BRD4_BD2_A-1390146

Released:
Source organism: Homo sapiens
Entry author: Park CH

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-130112 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bromodomain-containing protein 4 Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 12.81 KDa
Source organism: Homo sapiens
Expression system: Enterobacteria phage L1
UniProt:
  • Canonical: O60885 (Residues: 352-457; Coverage: 8%)
Gene names: BRD4, HUNK1
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21212
Unit cell:
a: 63.624Å b: 70.417Å c: 33.555Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.179 0.217
Expression system: Enterobacteria phage L1