› 5a42

Electron Microscopy
16Å resolution

Cryo-EM single particle 3D reconstruction of the native conformation of E. coli alpha-2-macroglobulin (ECAM)

Released:
DOI: 10.2210/pdb5a42/pdb
PDB entry 5a42 coloured by chain, front view.
PDB entry 5a42 coloured by chain, side view.
PDB entry 5a42 coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
Structural and functional insights into Escherichia coli α2-macroglobulin endopeptidase snap-trap inhibition.
Garcia-Ferrer I, Arêde P, Gómez-Blanco J, Luque D, Duquerroy S, Castón JR, Goulas T, Gomis-Rüth FX
Proc Natl Acad Sci U S A 112 8290-5 (2015)
PMID: 26100869
Related structures: EMD-3016

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160110 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 16Å
Relevant EMDB volumes: EMD-3016
Expression system: Escherichia coli BL21(DE3)

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Citations

2 review citations

Oxidation of proteins: is it a programmed process?
Rosenfeld et al. (2018)
1 more

4 mentions without citation

Ghrelin octanoylation by ghrelin O-acyltransferase: protein acylation impacting metabolic and neuroendocrine signalling.
Davis et al. (2021)
3 more