5a5u

Electron Microscopy
9Å resolution

Structure of mammalian eIF3 in the context of the 43S preinitiation complex

Released:
Source organism: Oryctolagus cuniculus
Related structures: EMD-3057

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-124212 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
EUKARYOTIC INITIATION FACTOR 3 Chain: A
Molecule details ›
Chain: A
Length: 54 amino acids
Theoretical weight: 4.61 KDa
Source organism: Oryctolagus cuniculus
Eukaryotic translation initiation factor 3 subunit B Chain: B
Molecule details ›
Chain: B
Length: 1121 amino acids
Theoretical weight: 124.4 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SZ03 (Residues: 1-679; Coverage: 100%)
Gene names: EIF3B, EIF3S9
Sequence domains:
Eukaryotic translation initiation factor 3 subunit I Chain: I
Molecule details ›
Chain: I
Length: 347 amino acids
Theoretical weight: 38.8 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P40217 (Residues: 1-347; Coverage: 100%)
Gene names: TIF34, YM9375.16C, YMR146C
Sequence domains: WD domain, G-beta repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-3057