Function and Biology

GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with PUGNAc

Source organism: Streptococcus pneumoniae TIGR4
Biochemical function: hydrolase activity
Biological process: carbohydrate metabolic process
Cellular component: not assigned

Sequence families

Pfam Protein families (Pfam)
PF18088
Domain description: Glycoside Hydrolase 20C C-terminal domain
Occurring in:
  1. Glycosyl hydrolase-related protein
  2. Glycosyl hydrolase-related protein
The deposited structure of PDB entry 5a6b contains 3 copies of Pfam domain PF18088 (Glycoside Hydrolase 20C C-terminal domain) in Glycosyl hydrolase-related protein. Showing 1 copy in chain B.
The deposited structure of PDB entry 5a6b contains 1 copy of Pfam domain PF18088 (Glycoside Hydrolase 20C C-terminal domain) in Glycosyl hydrolase-related protein. Showing 1 copy in chain D.

PF00728
Domain description: Glycosyl hydrolase family 20, catalytic domain
Occurring in:
  1. Glycosyl hydrolase-related protein
  2. Glycosyl hydrolase-related protein
The deposited structure of PDB entry 5a6b contains 3 copies of Pfam domain PF00728 (Glycosyl hydrolase family 20, catalytic domain) in Glycosyl hydrolase-related protein. Showing 1 copy in chain B.
The deposited structure of PDB entry 5a6b contains 1 copy of Pfam domain PF00728 (Glycosyl hydrolase family 20, catalytic domain) in Glycosyl hydrolase-related protein. Showing 1 copy in chain D.

PF18229
Domain description: N-acetyl-beta-D-glucosaminidase N-terminal domain
Occurring in:
  1. Glycosyl hydrolase-related protein
  2. Glycosyl hydrolase-related protein
The deposited structure of PDB entry 5a6b contains 3 copies of Pfam domain PF18229 (N-acetyl-beta-D-glucosaminidase N-terminal domain) in Glycosyl hydrolase-related protein. Showing 1 copy in chain B.
The deposited structure of PDB entry 5a6b contains 1 copy of Pfam domain PF18229 (N-acetyl-beta-D-glucosaminidase N-terminal domain) in Glycosyl hydrolase-related protein. Showing 1 copy in chain D.

InterPro InterPro annotations
IPR041063
Domain description: Glycoside Hydrolase 20C, C-terminal
Occurring in:
  1. Glycosyl hydrolase-related protein
  2. Glycosyl hydrolase-related protein
IPR017853
Domain description: Glycoside hydrolase superfamily
Occurring in:
  1. Glycosyl hydrolase-related protein
  2. Glycosyl hydrolase-related protein
IPR041272
Domain description: N-acetyl-beta-D-glucosaminidase, N-terminal
Occurring in:
  1. Glycosyl hydrolase-related protein
  2. Glycosyl hydrolase-related protein
IPR038901
Domain description: Hexosaminidase D-like
Occurring in:
  1. Glycosyl hydrolase-related protein
  2. Glycosyl hydrolase-related protein
IPR036393
Domain description: Acetylglutamate kinase-like superfamily
Occurring in:
  1. Glycosyl hydrolase-related protein
  2. Glycosyl hydrolase-related protein
IPR015883
Domain description: Glycoside hydrolase family 20, catalytic domain
Occurring in:
  1. Glycosyl hydrolase-related protein

Structure domains

CATH CATH domains
1.20.120.670
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Four Helix Bundle (Hemerythrin (Met), subunit A)
Homology: N-acetyl-b-d-glucoasminidase
Occurring in:
  1. Glycosyl hydrolase-related protein
  2. Glycosyl hydrolase-related protein
The deposited structure of PDB entry 5a6b contains 3 copies of CATH domain 1.20.120.670 (Four Helix Bundle (Hemerythrin (Met), subunit A)) in Glycosyl hydrolase-related protein. Showing 1 copy in chain B.
The deposited structure of PDB entry 5a6b contains 1 copy of CATH domain 1.20.120.670 (Four Helix Bundle (Hemerythrin (Met), subunit A)) in Glycosyl hydrolase-related protein. Showing 1 copy in chain D.
3.20.20.80
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Glycosidases
Occurring in:
  1. Glycosyl hydrolase-related protein
  2. Glycosyl hydrolase-related protein
The deposited structure of PDB entry 5a6b contains 3 copies of CATH domain 3.20.20.80 (TIM Barrel) in Glycosyl hydrolase-related protein. Showing 1 copy in chain B.
The deposited structure of PDB entry 5a6b contains 1 copy of CATH domain 3.20.20.80 (TIM Barrel) in Glycosyl hydrolase-related protein. Showing 1 copy in chain D.
3.30.160.230
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Double Stranded RNA Binding Domain
Homology: N-acetyl-beta-d-glucosaminidase
Occurring in:
  1. Glycosyl hydrolase-related protein
  2. Glycosyl hydrolase-related protein
The deposited structure of PDB entry 5a6b contains 3 copies of CATH domain 3.30.160.230 (Double Stranded RNA Binding Domain) in Glycosyl hydrolase-related protein. Showing 1 copy in chain B.
The deposited structure of PDB entry 5a6b contains 1 copy of CATH domain 3.30.160.230 (Double Stranded RNA Binding Domain) in Glycosyl hydrolase-related protein. Showing 1 copy in chain D.