› 5amo

X-ray diffraction
2.4Å resolution

Structure of a mouse Olfactomedin-1 disulfide-linked dimer of the Olfactomedin domain and part of the coiled coil

Released:
DOI: 10.2210/pdb5amo/pdb
PDB entry 5amo coloured by chain, front view.
PDB entry 5amo coloured by chain, side view.
PDB entry 5amo coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Olfactomedin-1 Has a V-shaped Disulfide-linked Tetrameric Structure.
Pronker MF, Bos TG, Sharp TH, Thies-Weesie DM, Janssen BJ
OpenAccess logo J Biol Chem 290 15092-101 (2015)
PMID: 25903135

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131599 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Noelin Chains: A, B
Molecule details ›
Chains: A, B
Length: 471 amino acids
Theoretical weight: 54.08 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: O88998 (Residues: 17-478; Coverage: 99%)
  • Best match: O88998-2 (Residues: 17-152)
Gene names: Noe1, Noel, Noel1, Olfm1
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
3 bound ligands:
Ligand NAG 2 x NAG
Ligand GOL 3 x GOL
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 160.22Å b: 43.94Å c: 104.06Å
α: 90° β: 114.17° γ: 90°
R-values:
R R work R free
0.238 0.237 0.258
Expression system: Homo sapiens

Quick links

Citations

9 citation in other articles

Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin.
Hill et al. (2017)
8 more

4 mentions without citation

Stitching the synapse: Cross-linking mass spectrometry into resolving synaptic protein interactions.
Gonzalez-Lozano et al. (2020)
3 more