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Crystal structure of a generation 4 influenza hemagglutinin stabilized stem in complex with the broadly neutralizing antibody CR6261

Source organisms:
Biochemical function: host cell surface receptor binding
Biological process: fusion of virus membrane with host plasma membrane
Cellular component: viral envelope

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00509
Domain description: Haemagglutinin
Occurring in:
  1. Fibritin C-terminal domain-containing protein; Hemagglutinin HA2 chain; Transmembrane protein gp41

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. CR6261 antibody heavy chain
  2. CR6261 antibody light chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. CR6261 antibody heavy chain
  2. CR6261 antibody light chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. CR6261 antibody heavy chain
  2. CR6261 antibody light chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. CR6261 antibody heavy chain
  2. CR6261 antibody light chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. CR6261 antibody heavy chain
  2. CR6261 antibody light chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. CR6261 antibody heavy chain
  2. CR6261 antibody light chain
IPR001364
Domain description: Haemagglutinin, influenzavirus A/B
Occurring in:
  1. Fibritin C-terminal domain-containing protein; Hemagglutinin HA2 chain; Transmembrane protein gp41
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. CR6261 antibody heavy chain
  2. CR6261 antibody light chain
IPR000149
Domain description: Haemagglutinin, influenzavirus A
Occurring in:
  1. Fibritin C-terminal domain-containing protein; Hemagglutinin HA2 chain; Transmembrane protein gp41
IPR012473
Domain description: Fibritin C-terminal
Occurring in:
  1. Fibritin C-terminal domain-containing protein; Hemagglutinin HA2 chain; Transmembrane protein gp41
IPR008980
Domain description: Viral capsid/haemagglutinin protein
Occurring in:
  1. Fibritin C-terminal domain-containing protein; Hemagglutinin HA2 chain; Transmembrane protein gp41

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