› 5cbg

X-ray diffraction
3.14Å resolution

Calcium activated non-selective cation channel

Released:
DOI: 10.2210/pdb5cbg/pdb
Model geometry
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PDB entry 5cbg coloured by chain, front view.
PDB entry 5cbg coloured by chain, side view.
PDB entry 5cbg coloured by chain, top view.
Source organism: Tsukamurella paurometabola DSM 20162
Primary publication:
Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola.
Dhakshnamoorthy B, Rohaim A, Rui H, Blachowicz L, Roux B
OpenAccess logo Nat Commun 7 12753 (2016)
PMID: 27678077

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112749 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel domain-containing protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 129 amino acids
Theoretical weight: 14.12 KDa
Source organism: Tsukamurella paurometabola DSM 20162
Expression system: Escherichia coli
UniProt:
  • Canonical: D5UM26 (Residues: 1-123; Coverage: 100%)
Gene name: Tpau_1687
Sequence domains: Ion channel
Structure domains: Helix Hairpins

Ligands and Environments

2 bound ligands:
Ligand CA 8 x CA
Ligand DMU 3 x DMU
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: I4
Unit cell:
a: 115.573Å b: 115.573Å c: 127.487Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.233 0.299
Expression system: Escherichia coli

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Citations

2 review citations

Polarizable Force Fields for Biomolecular Simulations: Recent Advances and Applications.
Jing et al. (2019)
1 more

1 mention without citation

Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola.
Dhakshnamoorthy et al. (2016)

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