› 5d4w

X-ray diffraction
3.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123986 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Clp R domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 926 amino acids
Theoretical weight: 103.85 KDa
Source organism: Chaetomium thermophilum
Expression system: Escherichia coli
UniProt:
  • Canonical: G0S4G4 (Residues: 1-926; Coverage: 100%)
Gene name: CTHT_0022720
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ADP 6 x ADP
1 modified residue:
Ligand MSE 66 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: OTHER
Spacegroup: P21
Unit cell:
a: 144.92Å b: 93.17Å c: 144.416Å
α: 90° β: 119.72° γ: 90°
R-values:
R R work R free
0.239 0.237 0.277
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Spiraling in Control: Structures and Mechanisms of the Hsp104 Disaggregase.
Shorter et al. (2019)
3 more

7 mentions without citation

Comparative Analysis of the Structure and Function of AAA+ Motors ClpA, ClpB, and Hsp104: Common Threads and Disparate Functions.
Duran et al. (2017)
6 more