› 5d5z

X-ray diffraction
1.7Å resolution

Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form II

Released:
DOI: 10.2210/pdb5d5z/pdb
PDB entry 5d5z coloured by chain, front view.
PDB entry 5d5z coloured by chain, side view.
PDB entry 5d5z coloured by chain, top view.
Source organism: Chaetomium thermophilum
Primary publication:
Structure of human heat-shock transcription factor 1 in complex with DNA.
Neudegger T, Verghese J, Hayer-Hartl M, Hartl FU, Bracher A
Nat Struct Mol Biol 23 140-6 (2016)
PMID: 26727489

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo trimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-124055 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor SKN7 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 50 amino acids
Theoretical weight: 5.71 KDa
Source organism: Chaetomium thermophilum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: G0SB31 (Residues: 160-209; Coverage: 7%)
Gene names: CTHT_0048700, SKN7

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21212
Unit cell:
a: 47.004Å b: 61.027Å c: 75.794Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.209 0.285
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

14 review citations

Regulation of heat shock transcription factors and their roles in physiology and disease.
Gomez-Pastor et al. (2018)
13 more

2 mentions without citation

Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1.
Hentze et al. (2016)
1 more