GO terms
Biochemical function:
Biological process:
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
- cell surface receptor signaling pathway via STAT
- dendritic cell differentiation
- cellular response to granulocyte macrophage colony-stimulating factor stimulus
- positive regulation of podosome assembly
- cellular response to lipopolysaccharide
- positive regulation of leukocyte proliferation
- negative regulation of DNA-templated transcription
- regulation of circadian sleep/wake cycle, sleep
- myeloid dendritic cell differentiation
- regulation of cell population proliferation
- epithelial fluid transport
- granulocyte-macrophage colony-stimulating factor signaling pathway
- response to fluid shear stress
- response to silicon dioxide
- positive regulation of interleukin-23 production
- positive regulation of cell migration
- macrophage differentiation
- monocyte differentiation
- neutrophil differentiation
- myeloid cell differentiation
- positive regulation of macrophage derived foam cell differentiation
- positive regulation of gene expression
- regulation of gene expression
- positive regulation of cell population proliferation
- cell population proliferation
- cell surface receptor signaling pathway via JAK-STAT
- immune response
- embryonic placenta development
- histamine secretion
Cellular component:
Sequence family
Protein family (Pfam)
InterPro annotations
IPR003006
Domain description:
Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
Occurring in:
CATH domains![The deposited structure of PDB entry 5d70 contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Immunglobulin G1 Fab fragment, heavy chain. Showing 2 copies in chain B [auth H].](https://www.ebi.ac.uk/pdbe/static/entry/5d70_2_H_CATH_2.60.40.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5d70</span> contains 2 copies of CATH domain <span class='highlight'>2.60.40.10 (Immunoglobulin-like)</span> in <span class='highlight'>Immunglobulin G1 Fab fragment, heavy chain</span>. Showing 2 copies in chain <span class='highlight'>B [auth H]</span>.")
![The deposited structure of PDB entry 5d70 contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Immunglobulin G1 Fab fragment, light chain. Showing 2 copies in chain C [auth L].](https://www.ebi.ac.uk/pdbe/static/entry/5d70_3_L_CATH_2.60.40.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5d70</span> contains 2 copies of CATH domain <span class='highlight'>2.60.40.10 (Immunoglobulin-like)</span> in <span class='highlight'>Immunglobulin G1 Fab fragment, light chain</span>. Showing 2 copies in chain <span class='highlight'>C [auth L]</span>.")
