Function and Biology

Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques

Source organism: Macaca mulatta
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN
  2. ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN
  2. ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN
  2. ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN
  2. ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN
  2. ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN
  2. ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN

Structure domain

CATH CATH domain
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN
  2. ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN
The deposited structure of PDB entry 5dd3 contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in ANTI-HIV ANTIBODY DH570.4 FAB HEAVY CHAIN. Showing 2 copies in chain A [auth H].
The deposited structure of PDB entry 5dd3 contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in ANTI-HIV ANTIBODY DH570.4 FAB LIGHT CHAIN. Showing 2 copies in chain B [auth L].