Function and Biology Details
Reactions catalysed:
1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol 3-phosphate + ethanolamine
A phosphatidylcholine + H(2)O = choline + a phosphatidate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Somatomedin B domain
- Somatomedin B domain, chordata
- DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain
- Alkaline-phosphatase-like, core domain superfamily
- Somatomedin B-like domain superfamily
- ENPP1-3/EXOG-like, endonuclease/phosphodiesterase domain
- His-Me finger superfamily
- DNA/RNA non-specific endonuclease superfamily
1 more domain
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Autotaxin (preferred)
PDBe Complex ID:
PDB-CPX-179148 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Autotaxin
Molecule details ›
Chain: A
Length: 827 amino acids
Theoretical weight: 95 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt: Gene names: Atx, Enpp2, Npps2
Sequence domains:
Length: 827 amino acids
Theoretical weight: 95 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt: Gene names: Atx, Enpp2, Npps2
Q64610Sequence domains:
- Somatomedin B domain
- Type I phosphodiesterase / nucleotide pyrophosphatase
- DNA/RNA non-specific endonuclease
