Function and Biology

The crystal structure of Arabidopsis 7-hydroxymethyl chlorophyll a reductase (HCAR)

Source organism: Arabidopsis thaliana
Biochemical function: 7-hydroxymethyl chlorophyll a reductase activity
Biological process: chlorophyll cycle
Cellular component: chloroplast

EC 1.17.7.2: 7-hydroxymethyl chlorophyll a reductase

Reaction catalysed:
Chlorophyll a + H(2)O + 2 oxidized ferredoxin = 7(1)-hydroxychlorophyll a + 2 reduced ferredoxin + 2 H(+)
Systematic name:
Chlorophyll-a:ferredoxin oxidoreductase
Alternative Name(s):
  • 7(1)-hydroxychlorophyll a:ferredoxin oxidoreductase
  • HCAR

Sequence families

Pfam Protein families (Pfam)
PF04432
Domain description: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
Occurring in:
  1. 7-hydroxymethyl chlorophyll a reductase, chloroplastic
The deposited structure of PDB entry 5dqr contains 6 copies of Pfam domain PF04432 (Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus) in 7-hydroxymethyl chlorophyll a reductase, chloroplastic. Showing 1 copy in chain C.

PF04422
Domain description: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term
Occurring in:
  1. 7-hydroxymethyl chlorophyll a reductase, chloroplastic
The deposited structure of PDB entry 5dqr contains 6 copies of Pfam domain PF04422 (Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term) in 7-hydroxymethyl chlorophyll a reductase, chloroplastic. Showing 1 copy in chain C.

InterPro InterPro annotations
IPR007525
Domain description: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal
Occurring in:
  1. 7-hydroxymethyl chlorophyll a reductase, chloroplastic
IPR007516
Domain description: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal
Occurring in:
  1. 7-hydroxymethyl chlorophyll a reductase, chloroplastic
IPR011254
Domain description: Prismane-like superfamily
Occurring in:
  1. 7-hydroxymethyl chlorophyll a reductase, chloroplastic
IPR045220
Domain description: Oxidoreductase FRHB/FDHB/HCAR-like
Occurring in:
  1. 7-hydroxymethyl chlorophyll a reductase, chloroplastic