› 5ebg

X-ray diffraction
1.8Å resolution

Crystal structure of bovine CD8aa homodimer

Released:
DOI: 10.2210/pdb5ebg/pdb
PDB entry 5ebg coloured by chain, front view.
PDB entry 5ebg coloured by chain, side view.
PDB entry 5ebg coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
The structural basis of chicken, swine and bovine CD8αα dimers provides insight into the co-evolution with MHC I in endotherm species.
Liu Y, Li X, Qi J, Zhang N, Xia C
OpenAccess logo Sci Rep 6 24788 (2016)
PMID: 27122108

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152092 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T-cell surface glycoprotein CD8 alpha chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 115 amino acids
Theoretical weight: 12.94 KDa
Source organism: Bos taurus
Expression system: Escherichia
UniProt:
  • Canonical: P31783 (Residues: 25-139; Coverage: 53%)
Gene name: CD8A
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: P6122
Unit cell:
a: 74.415Å b: 74.415Å c: 143.285Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.199 0.198 0.217
Expression system: Escherichia

Quick links

Citations

1 review citation

Integrating Experiment and Theory to Understand TCR-pMHC Dynamics.
Buckle et al. (2018)
4 other articles

2 mentions without citation

The structural basis of chicken, swine and bovine CD8αα dimers provides insight into the co-evolution with MHC I in endotherm species.
Liu et al. (2016)
1 more