› 5eg6

X-ray diffraction
2.09Å resolution

CSL-RITA complex bound to DNA

Released:
DOI: 10.2210/pdb5eg6/pdb
PDB entry 5eg6 coloured by chain, front view.
PDB entry 5eg6 coloured by chain, side view.
PDB entry 5eg6 coloured by chain, top view.
Source organisms:
Entry authors: Tabaja NH, Kovall RA

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-118630 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
Macromolecules (4 distinct):
Recombining binding protein suppressor of hairless Chain: C
Molecule details ›
Chain: C
Length: 422 amino acids
Theoretical weight: 47.87 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P31266 (Residues: 53-474; Coverage: 80%)
Gene names: Igkjrb1, Igkrsbp, Rbpj, Rbpsuh
Sequence domains:
Structure domains:
RBPJ-interacting and tubulin-associated protein 1 Chain: R
Molecule details ›
Chain: R
Length: 16 amino acids
Theoretical weight: 1.75 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: Q96K30 (Residues: 133-148; Coverage: 6%)
Gene names: C12orf52, PSEC0043, RITA, RITA1
DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3') Chain: B
Molecule details ›
Chain: B
Length: 15 nucleotides
Theoretical weight: 4.5 KDa
DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3') Chain: A
Molecule details ›
Chain: A
Length: 15 nucleotides
Theoretical weight: 4.67 KDa

Ligands and Environments

2 bound ligands:
Ligand EDO 19 x EDO
Ligand BU1 7 x BU1
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Unit cell:
a: 76.788Å b: 96.41Å c: 96.711Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.238
Expression systems:
  • Escherichia coli
  • Not provided

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