Function and Biology

Crystal structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with fragment-4 N10142 (SGC - Diamond I04-1 fragment screening)

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00439
Domain description: Bromodomain
Occurring in:
  1. PH-interacting protein
The deposited structure of PDB entry 5enf contains 1 copy of Pfam domain PF00439 (Bromodomain) in PH-interacting protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001487
Domain description: Bromodomain
Occurring in:
  1. PH-interacting protein
IPR036427
Domain description: Bromodomain-like superfamily
Occurring in:
  1. PH-interacting protein
IPR018359
Domain description: Bromodomain, conserved site
Occurring in:
  1. PH-interacting protein

Structure domain

CATH CATH domain
1.20.920.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Histone Acetyltransferase; Chain A
Homology: Bromodomain-like
Occurring in:
  1. PH-interacting protein
The deposited structure of PDB entry 5enf contains 1 copy of CATH domain 1.20.920.10 (Histone Acetyltransferase; Chain A) in PH-interacting protein. Showing 1 copy in chain A.