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Crystal Structure of chromodomain of CBX7 in complex with inhibitor UNC3866

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: PRC1 complex

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00385
Domain description: Chromo (CHRromatin Organisation MOdifier) domain
Occurring in:
  1. Chromobox protein homolog 7
The deposited structure of PDB entry 5epj contains 1 copy of Pfam domain PF00385 (Chromo (CHRromatin Organisation MOdifier) domain) in Chromobox protein homolog 7. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR017984
Domain description: Chromo domain subgroup
Occurring in:
  1. Chromobox protein homolog 7
IPR000953
Domain description: Chromo/chromo shadow domain
Occurring in:
  1. Chromobox protein homolog 7
IPR023779
Domain description: Chromo domain, conserved site
Occurring in:
  1. Chromobox protein homolog 7
IPR023780
Domain description: Chromo domain
Occurring in:
  1. Chromobox protein homolog 7
IPR016197
Domain description: Chromo-like domain superfamily
Occurring in:
  1. Chromobox protein homolog 7
IPR043531
Domain description: E3 SUMO-protein ligase CBX4
Occurring in:
  1. Chromobox protein homolog 7

Structure domain

CATH CATH domain
2.40.50.40
Class: Mainly Beta
Architecture: Beta Barrel
Topology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homology: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Occurring in:
  1. Chromobox protein homolog 7
The deposited structure of PDB entry 5epj contains 1 copy of CATH domain 2.40.50.40 (OB fold (Dihydrolipoamide Acetyltransferase, E2P)) in Chromobox protein homolog 7. Showing 1 copy in chain A.

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