› 5ezc

X-ray diffraction
1.8Å resolution

A de novo designed heptameric coiled coil CC-Hept-I18C-L22H-I25E

Released:
DOI: 10.2210/pdb5ezc/pdb
PDB entry 5ezc coloured by chain, front view.
PDB entry 5ezc coloured by chain, side view.
PDB entry 5ezc coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Installing hydrolytic activity into a completely de novo protein framework.
Burton AJ, Thomson AR, Dawson WM, Brady RL, Woolfson DN
Nat Chem 8 837-44 (2016)
PMID: 27554410

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165630 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CC-Hept-C-H-E Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 31 amino acids
Theoretical weight: 3.38 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Unit cell:
a: 62.252Å b: 60.88Å c: 69.38Å
α: 90° β: 110.89° γ: 90°
R-values:
R R work R free
0.189 0.187 0.22
Expression system: Not provided

Quick links

Citations

20 review citations

Coiled Coils - A Model System for the 21st Century.
Lupas et al. (2017)
19 more

5 mentions without citation

Catalytic peptide assemblies.
Zozulia et al. (2018)
4 more