5f3j

X-ray diffraction
4Å resolution

Crystal structure of DBP in complex with inhibitory monoclonal antibody 2D10

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-229916 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Duffy receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 317 amino acids
Theoretical weight: 37.61 KDa
Source organism: Plasmodium vivax Sal-1
Expression system: Escherichia coli
UniProt:
  • Canonical: P22290 (Residues: 211-525; Coverage: 30%)
Gene name: PVDR
Sequence domains: Duffy binding domain
Structure domains:
Antibody 2D10 single chain variable fragment Chains: C, D
Molecule details ›
Chains: C, D
Length: 305 amino acids
Theoretical weight: 32.23 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 84.94Å b: 63.94Å c: 108.88Å
α: 90° β: 100.09° γ: 90°
R-values:
R R work R free
0.269 0.267 0.3
Expression systems:
  • Escherichia coli
  • Homo sapiens