Function and Biology

HydE from T. maritima in complex with (2R,4R)-MeTDA

Source organism: Thermotoga maritima
Biochemical function: 4 iron, 4 sulfur cluster binding
Biological process: sulfur compound biosynthetic process
Cellular component: not assigned

Sequence family

Pfam Protein family (Pfam)
PF04055
Domain description: Radical SAM superfamily
Occurring in:
  1. [FeFe] hydrogenase maturase subunit HydE
The deposited structure of PDB entry 5fep contains 1 copy of Pfam domain PF04055 (Radical SAM superfamily) in [FeFe] hydrogenase maturase subunit HydE. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR007197
Domain description: Radical SAM
Occurring in:
  1. [FeFe] hydrogenase maturase subunit HydE
IPR010722
Domain description: Biotin and thiamin synthesis-associated domain
Occurring in:
  1. [FeFe] hydrogenase maturase subunit HydE
IPR024021
Domain description: [FeFe]-hydrogenase maturation HydE, radical SAM
Occurring in:
  1. [FeFe] hydrogenase maturase subunit HydE
IPR006638
Domain description: Elp3/MiaA/NifB-like, radical SAM core domain
Occurring in:
  1. [FeFe] hydrogenase maturase subunit HydE
IPR034422
Domain description: HydE/PylB-like
Occurring in:
  1. [FeFe] hydrogenase maturase subunit HydE
IPR013785
Domain description: Aldolase-type TIM barrel
Occurring in:
  1. [FeFe] hydrogenase maturase subunit HydE

Structure domain

CATH CATH domain
3.20.20.70
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Aldolase class I
Occurring in:
  1. [FeFe] hydrogenase maturase subunit HydE
The deposited structure of PDB entry 5fep contains 1 copy of CATH domain 3.20.20.70 (TIM Barrel) in [FeFe] hydrogenase maturase subunit HydE. Showing 1 copy in chain A.