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Crystal structure of GDP-bound aIF5B from Aeropyrum pernix

Source organism: Aeropyrum pernix K1
Biochemical function: GTP binding
Biological process: translational initiation
Cellular component: cytoplasm

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF14578
Domain description: Elongation factor Tu domain 4
Occurring in:
  1. Probable translation initiation factor IF-2
The deposited structure of PDB entry 5fg3 contains 1 copy of Pfam domain PF14578 (Elongation factor Tu domain 4) in Probable translation initiation factor IF-2. Showing 1 copy in chain A.

PF11987
Domain description: Translation-initiation factor 2
Occurring in:
  1. Probable translation initiation factor IF-2
The deposited structure of PDB entry 5fg3 contains 1 copy of Pfam domain PF11987 (Translation-initiation factor 2) in Probable translation initiation factor IF-2. Showing 1 copy in chain A.

PF03144
Domain description: Elongation factor Tu domain 2
Occurring in:
  1. Probable translation initiation factor IF-2
The deposited structure of PDB entry 5fg3 contains 1 copy of Pfam domain PF03144 (Elongation factor Tu domain 2) in Probable translation initiation factor IF-2. Showing 1 copy in chain A.

PF00009
Domain description: Elongation factor Tu GTP binding domain
Occurring in:
  1. Probable translation initiation factor IF-2
The deposited structure of PDB entry 5fg3 contains 1 copy of Pfam domain PF00009 (Elongation factor Tu GTP binding domain) in Probable translation initiation factor IF-2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000795
Domain description: Translational (tr)-type GTP-binding domain
Occurring in:
  1. Probable translation initiation factor IF-2
IPR036925
Domain description: Translation initiation factor IF-2, domain 3 superfamily
Occurring in:
  1. Probable translation initiation factor IF-2
IPR004544
Domain description: Translation initiation factor aIF-2, archaea
Occurring in:
  1. Probable translation initiation factor IF-2
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Probable translation initiation factor IF-2
IPR029459
Domain description: Elongation factor Tu-type domain
Occurring in:
  1. Probable translation initiation factor IF-2
IPR009000
Domain description: Translation protein, beta-barrel domain superfamily
Occurring in:
  1. Probable translation initiation factor IF-2
IPR023115
Domain description: Translation initiation factor IF- 2, domain 3
Occurring in:
  1. Probable translation initiation factor IF-2
IPR004161
Domain description: Translation elongation factor EFTu-like, domain 2
Occurring in:
  1. Probable translation initiation factor IF-2
IPR005225
Domain description: Small GTP-binding domain
Occurring in:
  1. Probable translation initiation factor IF-2
IPR015760
Domain description: Translation initiation factor IF- 2
Occurring in:
  1. Probable translation initiation factor IF-2

Structure domains

CATH CATH domains
3.40.50.10050
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Translation initiation factor IF- 2, domain 3
Occurring in:
  1. Probable translation initiation factor IF-2
The deposited structure of PDB entry 5fg3 contains 1 copy of CATH domain 3.40.50.10050 (Rossmann fold) in Probable translation initiation factor IF-2. Showing 1 copy in chain A.
2.40.30.10
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Elongation Factor Tu (Ef-tu); domain 3
Homology: Translation factors
Occurring in:
  1. Probable translation initiation factor IF-2
The deposited structure of PDB entry 5fg3 contains 1 copy of CATH domain 2.40.30.10 (Elongation Factor Tu (Ef-tu); domain 3) in Probable translation initiation factor IF-2. Showing 1 copy in chain A.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Probable translation initiation factor IF-2
The deposited structure of PDB entry 5fg3 contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in Probable translation initiation factor IF-2. Showing 1 copy in chain A.

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