5flx

Electron Microscopy
3.9Å resolution

Function and Biology Details

Reaction catalysed:
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 35-mer (preferred)
PDBe Complex ID:
PDB-CPX-140329 (preferred)
Entry contents:
33 distinct polypeptide molecules
2 distinct RNA molecules
Macromolecules (35 distinct):
Small ribosomal subunit protein uS2 Chain: A
Molecule details ›
Chain: A
Length: 295 amino acids
Theoretical weight: 32.88 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P08865 (Residues: 1-295; Coverage: 100%)
Gene names: LAMBR, LAMR1, RPSA
Sequence domains:
Structure domains: Glucose-6-phosphate isomerase like protein; domain 1
Small ribosomal subunit protein eS1 Chain: B
Molecule details ›
Chain: B
Length: 264 amino acids
Theoretical weight: 30 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P61247 (Residues: 1-264; Coverage: 100%)
Gene names: FTE1, MFTL, RPS3A
Sequence domains: Ribosomal S3Ae family
Small ribosomal subunit protein uS5 Chain: C
Small ribosomal subunit protein uS3 Chain: D
Small ribosomal subunit protein eS4, Y isoform 1 Chain: E
Small ribosomal subunit protein uS7 Chain: F
Small ribosomal subunit protein eS6 Chain: G
Small ribosomal subunit protein eS7 Chain: H
Small ribosomal subunit protein eS8 Chain: I
Small ribosomal subunit protein uS4 Chain: J
Small ribosomal subunit protein eS10 Chain: K
Small ribosomal subunit protein uS17 Chain: L
Small ribosomal subunit protein eS12 Chain: M
Small ribosomal subunit protein uS15 Chain: N
Small ribosomal subunit protein uS11 Chain: O
Small ribosomal subunit protein uS19 Chain: P
Small ribosomal subunit protein uS9 Chain: Q
Small ribosomal subunit protein eS17 Chain: R
Small ribosomal subunit protein uS13 Chain: S
Small ribosomal subunit protein eS19 Chain: T
Small ribosomal subunit protein uS10 Chain: U
Small ribosomal subunit protein eS21 Chain: V
Small ribosomal subunit protein uS8 Chain: W
Small ribosomal subunit protein uS12 Chain: X
Small ribosomal subunit protein eS24 Chain: Y
Small ribosomal subunit protein eS25 Chain: Z
Small ribosomal subunit protein eS26 Chain: a
Small ribosomal subunit protein eS27 Chain: b
Small ribosomal subunit protein eS28 Chain: c
Small ribosomal subunit protein uS14 Chain: d
Small ribosomal subunit protein eS30 Chain: e
Ubiquitin-ribosomal protein eS31 fusion protein Chain: f
Small ribosomal subunit protein RACK1 Chain: g
18S Ribosomal RNA Chain: 1
HCV-IRES Chain: z

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-3221