5fph

X-ray diffraction
3.2Å resolution

The GTPase domains of the immunity-related Irga6 dimerize in a parallel head-to-head fashion

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
monomeric
PDBe Complex ID:
PDB-CPX-193064 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon-inducible GTPase 1 Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 423 amino acids
Theoretical weight: 48.97 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9QZ85 (Residues: 1-413; Coverage: 100%)
Gene names: Iigp1, Irga6
Sequence domains: Interferon-inducible GTPase (IIGP)
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, DESY BEAMLINE P11
Spacegroup: P6122
Unit cell:
a: 98.51Å b: 98.51Å c: 1,289.4Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.298 0.297 0.317
Expression system: Escherichia coli BL21(DE3)