› 5frg

Solution NMR

The NMR Structure of the Cdc42-interacting region of TOCA1

Released:
DOI: 10.2210/pdb5frg/pdb
PDB entry 5frg coloured by chain, ensemble of 35 models, front view.
PDB entry 5frg coloured by chain, ensemble of 35 models, side view.
PDB entry 5frg coloured by chain, ensemble of 35 models, top view.
Source organism: Xenopus tropicalis
Primary publication:
Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES.
Watson JR, Fox HM, Nietlispach D, Gallop JL, Owen D, Mott HR
OpenAccess logo J Biol Chem 291 13875-90 (2016)
PMID: 27129201

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179715 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Formin-binding protein 1-like Chain: A
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 12.11 KDa
Source organism: Xenopus tropicalis
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q6GUF4 (Residues: 330-426; Coverage: 18%)
Gene names: TEgg061f15.1, fnbp1l, toca1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: ARIA2.3; CNS 1.2
Expression system: Escherichia coli BL21

Quick links

Citations

6 review citations

BAR domain proteins-a linkage between cellular membranes, signaling pathways, and the actin cytoskeleton.
Carman et al. (2018)
5 more

1 mention without citation

Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES.
Watson et al. (2016)