5ggr

X-ray diffraction
3.3Å resolution

PD-1 in complex with nivolumab Fab

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-212030 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
heavy chain Chains: A, H
Molecule details ›
Chains: A, H
Length: 225 amino acids
Theoretical weight: 24.28 KDa
Source organism: Homo sapiens
Expression system: Not provided
Structure domains: Immunoglobulins
light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 214 amino acids
Theoretical weight: 23.4 KDa
Source organism: Homo sapiens
Expression system: Not provided
Structure domains: Immunoglobulins
Programmed cell death protein 1 Chains: Y, Z

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P21
Unit cell:
a: 91.29Å b: 48.612Å c: 134.904Å
α: 90° β: 102.12° γ: 90°
R-values:
R R work R free
0.224 0.222 0.268
Expression systems:
  • Not provided
  • Escherichia coli-Pichia pastoris shuttle vector pPpARG4