EC 5.2.1.8: Peptidylprolyl isomerase
Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0)
Systematic name:
Peptidylproline cis-trans-isomerase
Alternative Name(s):
- Cyclophilin
- PPIase
- Peptide bond isomerase
- Peptidyl-prolyl cis-trans isomerase
- Peptidylprolyl cis-trans isomerase
- Rotamase
GO terms
Biochemical function:
Biological process:
- regulation of ryanodine-sensitive calcium-release channel activity
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
- protein peptidyl-prolyl isomerization
- cellular response to caffeine
- cellular response to calcium ion
- calcium ion transmembrane transport
- transmembrane transport
- protein homotetramerization
- release of sequestered calcium ion into cytosol
- skeletal muscle fiber development
- ossification involved in bone maturation
- skin development
- calcium-mediated signaling
- release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
- striated muscle contraction
- muscle contraction
- intracellular calcium ion homeostasis
- calcium ion transport
- monoatomic ion transport
- outflow tract morphogenesis