5gxp

X-ray diffraction
2.8Å resolution

Cationic Trypsin With GOL/PGE as Dimer at pH 4.6

Released:
Source organism: Bos taurus
Entry authors: Manohar R, Gunasekaran K

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133362 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine protease 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Gene names: PRSS1, TRP1, TRY1, TRYP1
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P212121
Unit cell:
a: 60.84Å b: 102.59Å c: 115.71Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.279 0.275 0.309
Expression system: Not provided