› 5h0t

X-ray diffraction
2.73Å resolution

Crystal structure of proliferating cell nuclear antigen from Leishmania donovani at 2.73 Angstrom resolution

Released:
DOI: 10.2210/pdb5h0t/pdb
PDB entry 5h0t coloured by chain, front view.
PDB entry 5h0t coloured by chain, side view.
PDB entry 5h0t coloured by chain, top view.
Source organism: Leishmania donovani
Primary publication:
Structure and binding studies of proliferating cell nuclear antigen from Leishmania donovani.
Yadav SP, Singh PK, Sharma P, Iqbal N, Kaur P, Sharma S, Singh TP
Biochim Biophys Acta Proteins Proteom 1865 1395-1405 (2017)
PMID: 28844736

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-110240 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proliferating cell nuclear antigen Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 292 amino acids
Theoretical weight: 32.19 KDa
Source organism: Leishmania donovani
Expression system: Escherichia coli
UniProt:
  • Canonical: B5TV91 (Residues: 1-292; Coverage: 100%)
Gene name: PCNA
Sequence domains:
Structure domains: Proliferating Cell Nuclear Antigen

Ligands and Environments

1 bound ligand:
Ligand PEG 2 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P212121
Unit cell:
a: 133.8Å b: 149.574Å c: 169.245Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.197 0.239
Expression system: Escherichia coli

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