› 5h5m

X-ray diffraction
2.4Å resolution

Crystal structure of HMP-1 M domain

Released:
DOI: 10.2210/pdb5h5m/pdb
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PDB entry 5h5m coloured by chain, front view.
PDB entry 5h5m coloured by chain, side view.
PDB entry 5h5m coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
Structural and functional characterization of Caenorhabditis elegans α-catenin reveals constitutive binding to β-catenin and F-actin.
Kang H, Bang I, Jin KS, Lee B, Lee J, Shao X, Heier JA, Kwiatkowski AV, Nelson WJ, Hardin J, Weis WI, Choi HJ
J Biol Chem 292 7077-7086 (2017)
PMID: 28298447

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161043 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-catenin-like protein hmp-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 381 amino acids
Theoretical weight: 42.86 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: P90947 (Residues: 270-646; Coverage: 41%)
Gene names: R13H4.4, hmp-1
Sequence domains: Vinculin family
Structure domains: Alpha-catenin/vinculin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P212121
Unit cell:
a: 72.849Å b: 81.532Å c: 151.386Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.203 0.248
Expression system: Escherichia coli

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Citations

2 review citations

Putting VE-cadherin into JAIL for junction remodeling.
Cao et al. (2019)
1 more

2 mentions without citation

Structural and functional characterization of Caenorhabditis elegans α-catenin reveals constitutive binding to β-catenin and F-actin.
Kang et al. (2017)
1 more

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