Function and Biology

p73 homo-tetramerization domain mutant I

Source organism: Homo sapiens
Biochemical function: DNA-binding transcription factor activity
Biological process: protein tetramerization
Cellular component: nucleus

Sequence family

Pfam Protein family (Pfam)
PF07710
Domain description: P53 tetramerisation motif
Occurring in:
  1. Tumor protein p73
The deposited structure of PDB entry 5hob contains 8 copies of Pfam domain PF07710 (P53 tetramerisation motif) in Tumor protein p73. Showing 1 copy in chain E.

InterPro InterPro annotations
IPR036674
Domain description: p53-like tetramerisation domain superfamily
Occurring in:
  1. Tumor protein p73
IPR010991
Domain description: p53, tetramerisation domain
Occurring in:
  1. Tumor protein p73
IPR002117
Domain description: p53 tumour suppressor family
Occurring in:
  1. Tumor protein p73

Structure domain

CATH CATH domain
4.10.170.10
Class: Few Secondary Structures
Architecture: Irregular
Topology: p53, subunit A
Homology: p53-like tetramerisation domain
Occurring in:
  1. Tumor protein p73
The deposited structure of PDB entry 5hob contains 8 copies of CATH domain 4.10.170.10 (p53, subunit A) in Tumor protein p73. Showing 1 copy in chain E.