› 5hqf

Solution NMR

DNA duplex containing a ribonolactone lesion

Released:
DOI: 10.2210/pdb5hqf/pdb
PDB entry 5hqf coloured by chain, ensemble of 10 models, front view.
PDB entry 5hqf coloured by chain, ensemble of 10 models, side view.
PDB entry 5hqf coloured by chain, ensemble of 10 models, top view.
Source organism: synthetic construct
Primary publication:
Nuclear Magnetic Resonance Solution Structure of DNA Featuring Clustered 2'-Deoxyribonolactone and 8-Oxoguanine Lesions.
Zálešák J, Constant JF, Jourdan M
Biochemistry 55 3899-906 (2016)
PMID: 27322640

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-118752 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*CP*GP*CP*TP*CP*(RIB)P*CP*AP*CP*GP*C)-3') Chain: A
Molecule details ›
Chain: A
Length: 11 nucleotides
Theoretical weight: 3.16 KDa
Source organism: synthetic construct
Expression system: Not provided
DNA (5'-D(*GP*CP*GP*TP*GP*GP*GP*AP*(8OG)P*CP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 11 nucleotides
Theoretical weight: 3.47 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand 8OG 1 x 8OG

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 43%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

4 citation in other articles

Correlation of bistranded clustered abasic DNA lesion processing with structural and dynamic DNA helix distortion.
Bignon et al. (2016)
3 more