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5hxb Overview
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5hxb</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Eukaryotic peptide chain release factor GTP-binding subunit ERF3A</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>DNA damage-binding protein 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>Protein cereblon</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5hxb_deposited_chain_front_image-800x800.png "PDB entry 5hxb coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5hxb</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Eukaryotic peptide chain release factor GTP-binding subunit ERF3A</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>DNA damage-binding protein 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>Protein cereblon</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5hxb_deposited_chain_side_image-800x800.png "PDB entry 5hxb coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5hxb</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Eukaryotic peptide chain release factor GTP-binding subunit ERF3A</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>DNA damage-binding protein 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>Protein cereblon</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5hxb_deposited_chain_top_image-800x800.png "PDB entry 5hxb coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5hxb</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Eukaryotic peptide chain release factor GTP-binding subunit ERF3A</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>DNA damage-binding protein 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>Protein cereblon</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5hxb_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 5hxb coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5hxb</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Eukaryotic peptide chain release factor GTP-binding subunit ERF3A</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>DNA damage-binding protein 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>Protein cereblon</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5hxb_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 5hxb coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>5hxb</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Eukaryotic peptide chain release factor GTP-binding subunit ERF3A</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>DNA damage-binding protein 1</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>Protein cereblon</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5hxb_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 5hxb coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Hetero trimeric assembly 2 of PDB entry <span class='highlight'>5hxb</span> contains 1 copy of <span class='highlight'>1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea</span>. Front view.</div>](https://www.ebi.ac.uk/pdbe/static/entry/5hxb_entity_5_front_image-800x800.png "1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea in PDB entry 5hxb, assembly 2, front view.")
![<div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>5hxb</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Eukaryotic peptide chain release factor GTP-binding subunit ERF3A</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DNA damage-binding protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Protein cereblon</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5hxb_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Hetero trimeric assembly 1 of PDB entry 5hxb coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>5hxb</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Eukaryotic peptide chain release factor GTP-binding subunit ERF3A</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DNA damage-binding protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Protein cereblon</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5hxb_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Hetero trimeric assembly 1 of PDB entry 5hxb coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Hetero trimeric assembly 1 of PDB entry <span class='highlight'>5hxb</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>1 copy of <span class='highlight'>Eukaryotic peptide chain release factor GTP-binding subunit ERF3A</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>DNA damage-binding protein 1</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>Protein cereblon</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>ZINC ION</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/5hxb_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Hetero trimeric assembly 1 of PDB entry 5hxb coloured by chemically distinct molecules, top view.")