› › Structure analysis

X-RAY CRYSTAL STRUCTURE AT 1.94A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A THIENOPYRIMIDINE COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR.

X-ray diffraction
1.94Å resolution
PDB entry 5i5v coloured by chain, front view.
PDB entry 5i5v coloured by chain, side view.
PDB entry 5i5v coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Branched-chain-amino-acid aminotransferase, mitochondrial
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 27391.33 Å2
Buried surface area: 9743.06 Å2
Dissociation area: 2,830.73 Å2
Dissociation energy (ΔGdiss): 20.97 kcal/mol
Dissociation entropy (TΔSdiss): 14.47 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-127454

Macromolecules

Branched-chain-amino-acid aminotransferase, mitochondrial
Chains: A, B
Length: 369 amino acids
Theoretical weight: 41.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15382 (Residues: 28-392; Coverage: 93%)
Gene names: BCAT2, BCATM, BCT2, ECA40
Pfam: Amino-transferase class IV
InterPro:
CATH:
Branched-chain-amino-acid aminotransferase, mitochondrial in PDB entry 5i5v, assembly 1, front view.
Branched-chain-amino-acid aminotransferase, mitochondrial in PDB entry 5i5v, assembly 1, side view.
Branched-chain-amino-acid aminotransferase, mitochondrial in PDB entry 5i5v, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links