5i70

X-ray diffraction
3Å resolution

Crystal Structure of plasmepsin IV

Released:
Entry author: Asojo OA

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-165773 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Peptidase A1 domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 328 amino acids
Theoretical weight: 36.99 KDa
Source organism: Plasmodium falciparum 7G8
Expression system: Escherichia coli
UniProt:
  • Canonical: W7FF86 (Residues: 122-449; Coverage: 73%)
Gene name: PFBG_05102
Sequence domains: Eukaryotic aspartyl protease
Structure domains: Acid Proteases
Pepstatin A Chains: C, D
Molecule details ›
Chains: C, D
Length: 6 amino acids
Theoretical weight: 686 Da
Source organism: Actinomyces
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P3121
Unit cell:
a: 103.42Å b: 103.42Å c: 123.69Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.251 0.248 0.294
Expression systems:
  • Escherichia coli
  • Not provided