› 5i72

X-ray diffraction
2.9Å resolution

Crystal structure of the oligomeric form of the Lassa virus matrix protein Z

Released:
DOI: 10.2210/pdb5i72/pdb
PDB entry 5i72 coloured by chain, front view.
PDB entry 5i72 coloured by chain, side view.
PDB entry 5i72 coloured by chain, top view.
Source organism: Lassa virus Josiah
Primary publication:
Crystal Structure of the Oligomeric Form of Lassa Virus Matrix Protein Z.
Hastie KM, Zandonatti M, Liu T, Li S, Woods VL, Saphire EO
J Virol 90 4556-62 (2016)
PMID: 26912609

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130724 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RING finger protein Z Chains: A, B
Molecule details ›
Chains: A, B
Length: 53 amino acids
Theoretical weight: 6.09 KDa
Source organism: Lassa virus Josiah
Expression system: Escherichia coli
UniProt:
  • Canonical: O73557 (Residues: 25-77; Coverage: 54%)
Gene name: Z
Sequence domains: P-11 zinc finger

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: R32
Unit cell:
a: 116.961Å b: 116.961Å c: 82.544Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.191 0.19 0.209
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Lassa fever - the road ahead.
Garry RF. (2023)
3 more

4 mentions without citation

Multiple origins of viral capsid proteins from cellular ancestors.
Krupovic et al. (2017)
3 more