Function and Biology

Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Ca2+ complex

Source organisms:
Biochemical function: catalytic activity
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF03372
Domain description: Endonuclease/Exonuclease/phosphatase family
Occurring in:
  1. Tyrosyl-DNA phosphodiesterase 2
The deposited structure of PDB entry 5inq contains 2 copies of Pfam domain PF03372 (Endonuclease/Exonuclease/phosphatase family) in Tyrosyl-DNA phosphodiesterase 2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR036691
Domain description: Endonuclease/exonuclease/phosphatase superfamily
Occurring in:
  1. Tyrosyl-DNA phosphodiesterase 2
IPR005135
Domain description: Endonuclease/exonuclease/phosphatase
Occurring in:
  1. Tyrosyl-DNA phosphodiesterase 2

Structure domain

CATH CATH domain
3.60.10.10
Class: Alpha Beta
Architecture: 4-Layer Sandwich
Topology: Deoxyribonuclease I; Chain A
Homology: Endonuclease/exonuclease/phosphatase
Occurring in:
  1. Tyrosyl-DNA phosphodiesterase 2
The deposited structure of PDB entry 5inq contains 2 copies of CATH domain 3.60.10.10 (Deoxyribonuclease I; Chain A) in Tyrosyl-DNA phosphodiesterase 2. Showing 1 copy in chain A.