5ix1

X-ray diffraction
2.6Å resolution

Crystal structure of mouse Morc3 ATPase-CW cassette in complex with AMPPNP and H3K4me3 peptide

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-514622 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
MORC family CW-type zinc finger protein 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 451 amino acids
Theoretical weight: 51.95 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: F7BJB9 (Residues: 7-456; Coverage: 48%)
Gene names: Morc3, Nxp2, Zcwcc3
Sequence domains:
Structure domains: Herpes Virus-1
Histone H3.1 Chains: P, Q
Molecule details ›
Chains: P, Q
Length: 15 amino acids
Theoretical weight: 1.61 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P68433 (Residues: 2-16; Coverage: 11%)
Gene names: H3.1-221, H3.1-291, H3.1-I, H3a, H3c1, H3c10, H3c11, H3c8, H3g, H3h, H3i, Hist1h3a, Hist1h3g, Hist1h3h, Hist1h3i

Ligands and Environments

3 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: I222
Unit cell:
a: 111.353Å b: 149.079Å c: 173.473Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.218 0.23
Expression systems:
  • Escherichia coli
  • Not provided