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RORgamma in complex with agonist BIO592 and Coactivator EBI96

Source organism: Homo sapiens
Biochemical function: nuclear receptor activity
Biological process: regulation of DNA-templated transcription
Cellular component: nucleus

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00104
Domain description: Ligand-binding domain of nuclear hormone receptor
Occurring in:
  1. Nuclear receptor ROR-gamma
The deposited structure of PDB entry 5iz0 contains 4 copies of Pfam domain PF00104 (Ligand-binding domain of nuclear hormone receptor) in Nuclear receptor ROR-gamma. Showing 1 copy in chain G.

InterPro InterPro annotations
IPR001723
Domain description: Nuclear hormone receptor
Occurring in:
  1. Nuclear receptor ROR-gamma
IPR003079
Domain description: Nuclear receptor ROR
Occurring in:
  1. Nuclear receptor ROR-gamma
IPR000536
Domain description: Nuclear hormone receptor, ligand-binding domain
Occurring in:
  1. Nuclear receptor ROR-gamma
IPR035500
Domain description: Nuclear hormone receptor-like domain superfamily
Occurring in:
  1. Nuclear receptor ROR-gamma

Structure domain

CATH CATH domain
1.10.565.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Retinoid X Receptor
Homology: Retinoid X Receptor
Occurring in:
  1. Nuclear receptor ROR-gamma
The deposited structure of PDB entry 5iz0 contains 4 copies of CATH domain 1.10.565.10 (Retinoid X Receptor) in Nuclear receptor ROR-gamma. Showing 1 copy in chain G.

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