› 5jkq

X-ray diffraction
2.35Å resolution

Crystal structure of Plasmodium falciparum Pf3D7_0606800 (PfVFT1)

Released:
DOI: 10.2210/pdb5jkq/pdb
PDB entry 5jkq coloured by chain, front view.
PDB entry 5jkq coloured by chain, side view.
PDB entry 5jkq coloured by chain, top view.
Source organism: Plasmodium falciparum 3D7
Primary publication:
The structure of Plasmodium falciparum 3D7_0606800 reveals a bi-lobed architecture that supports re-annotation as a Venus Flytrap protein.
Parker ML, Ramaswamy R, van Gordon K, Powell CJ, Bosch J, Boulanger MJ
Protein Sci 26 1878-1885 (2017)
PMID: 28681555

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo octamer
Assembly name:
PDBe Complex ID:
PDB-CPX-111602 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
VFT protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 284 amino acids
Theoretical weight: 32.5 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Trichoplusia ni
UniProt:
  • Canonical: C6KSR6 (Residues: 23-299; Coverage: 98%)
Gene name: PF3D7_0606800

Ligands and Environments

1 bound ligand:
Ligand SO4 6 x SO4
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P21212
Unit cell:
a: 84.77Å b: 201.43Å c: 77.56Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.204 0.261
Expression system: Trichoplusia ni

Quick links

Citations

1 citations in other articles

In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration.
Sangaré et al. (2019)

1 mention without citation

The structure of Plasmodium falciparum 3D7_0606800 reveals a bi-lobed architecture that supports re-annotation as a Venus Flytrap protein.
Parker et al. (2017)