› 5jzd

X-ray diffraction
2.3Å resolution

A re-refinement of the isochorismate synthase EntC

Released:
DOI: 10.2210/pdb5jzd/pdb
PDB entry 5jzd coloured by chain, front view.
PDB entry 5jzd coloured by chain, side view.
PDB entry 5jzd coloured by chain, top view.
Source organism: Escherichia coli K-12
Primary publication:
An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
Meneely KM, Sundlov JA, Gulick AM, Moran GR, Lamb AL
OpenAccess logo J Am Chem Soc 138 9277-93 (2016)
PMID: 27373320

Function and Biology Details

Reaction catalysed: 
Chorismate = isochorismate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142462 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Isochorismate synthase EntC Chains: A, B
Molecule details ›
Chains: A, B
Length: 391 amino acids
Theoretical weight: 42.98 KDa
Source organism: Escherichia coli K-12
Expression system: Not provided
UniProt:
  • Canonical: P0AEJ2 (Residues: 1-391; Coverage: 100%)
Gene names: JW0585, b0593, entC
Sequence domains: chorismate binding enzyme
Structure domains: Anthranilate synthase

Ligands and Environments

2 bound ligands:
Ligand ISC 2 x ISC
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 62.469Å b: 104.795Å c: 140.014Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.195 0.256
Expression system: Not provided

Quick links

Citations

3 review citations

Nonribosomal peptides for iron acquisition: pyochelin biosynthesis as a case study.
Ronnebaum et al. (2018)
2 more

1 mention without citation

An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
Meneely et al. (2016)