› 5k1s

X-ray diffraction
2.55Å resolution

crystal structure of AibC

Released:
DOI: 10.2210/pdb5k1s/pdb
PDB entry 5k1s coloured by chain, front view.
PDB entry 5k1s coloured by chain, side view.
PDB entry 5k1s coloured by chain, top view.
Source organism: Myxococcus xanthus DK 1622
Primary publication:
Crystal structure of AibC, a reductase involved in alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus.
Bock T, Müller R, Blankenfeldt W
Acta Crystallogr F Struct Biol Commun 72 652-8 (2016)
PMID: 27487931

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172799 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enoyl reductase (ER) domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 362 amino acids
Theoretical weight: 38.23 KDa
Source organism: Myxococcus xanthus DK 1622
Expression system: Escherichia coli
UniProt:
  • Canonical: Q1D4I2 (Residues: 1-345; Coverage: 100%)
Gene name: MXAN_4266
Sequence domains:
Structure domains: Medium-chain alcohol dehydrogenases, catalytic domain

Ligands and Environments

1 bound ligand:
Ligand ZN 8 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 77.294Å b: 77.427Å c: 309.638Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.234 0.269
Expression system: Escherichia coli

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Citations

1 citations in other articles

AibA/AibB Induces an Intramolecular Decarboxylation in Isovalerate Biosynthesis by Myxococcus xanthus.
Bock et al. (2017)