GO terms
Biochemical function:
- metal ion binding
- GTPase activating protein binding
- G protein-coupled serotonin receptor binding
- D2 dopamine receptor binding
- G-protein beta/gamma-subunit complex binding
- GDP binding
- guanyl nucleotide binding
- hydrolase activity
- adenylate cyclase regulator activity
- GTP binding
- protein binding
- G protein activity
- GTPase activity
- G protein-coupled receptor binding
- magnesium ion binding
- nucleotide binding
Biological process:
- positive regulation of protein localization to cell cortex
- cellular response to forskolin
- neurotransmitter receptor localization to postsynaptic specialization membrane
- T cell migration
- regulation of mitotic spindle organization
- cell division
- negative regulation of synaptic transmission
- positive regulation of cholesterol biosynthetic process
- response to prostaglandin E
- adenylate cyclase-inhibiting serotonin receptor signaling pathway
- adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
- adenylate cyclase-modulating G protein-coupled receptor signaling pathway
- G protein-coupled receptor signaling pathway
- signal transduction
Cellular component:
Sequence family
Protein family (Pfam)
InterPro annotations
IPR001019
Domain description:
Guanine nucleotide binding protein (G-protein), alpha subunit
Occurring in:
Occurring in:
Structure domains
CATH domains
3.40.50.300
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Rossmann fold
Homology:
P-loop containing nucleotide triphosphate hydrolases
Occurring in:
