Assemblies
Assembly Name:
Importin subunit alpha-1 and peptide
Multimeric state:
hetero dimer
Accessible surface area:
18500.18 Å2
Buried surface area:
1341.18 Å2
Dissociation area:
670.59
Å2
Dissociation energy (ΔGdiss):
1.5
kcal/mol
Dissociation entropy (TΔSdiss):
7.3
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-546860
Macromolecules
Chain: B
Length: 510 amino acids
Theoretical weight: 55.27 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
InterPro:
CATH: Leucine-rich Repeat Variant
Length: 510 amino acids
Theoretical weight: 55.27 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P52293 (Residues: 70-529; Coverage: 87%)
Pfam:
InterPro:
CATH: Leucine-rich Repeat Variant
Chain: A
Length: 16 amino acids
Theoretical weight: 1.7 KDa
Source organism: synthetic construct
Expression system: Escherichia coli BL21(DE3)
Length: 16 amino acids
Theoretical weight: 1.7 KDa
Source organism: synthetic construct
Expression system: Escherichia coli BL21(DE3)
![Prototypical P4[M]cNLS in PDB entry 5klt, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/5klt_entity_2_front_image-200x200.png "Hetero dimeric assembly 1 of PDB entry <span class='highlight'>5klt</span> contains 1 copy of <span class='highlight'>Prototypical P4[M]cNLS</span>. Front view.")
![Prototypical P4[M]cNLS in PDB entry 5klt, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/5klt_entity_2_side_image-200x200.png "Hetero dimeric assembly 1 of PDB entry <span class='highlight'>5klt</span> contains 1 copy of <span class='highlight'>Prototypical P4[M]cNLS</span>. Side view.")
![Prototypical P4[M]cNLS in PDB entry 5klt, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/5klt_entity_2_top_image-200x200.png "Hetero dimeric assembly 1 of PDB entry <span class='highlight'>5klt</span> contains 1 copy of <span class='highlight'>Prototypical P4[M]cNLS</span>. Top view.")