EC 3.2.2.31: Adenine glycosylase
Reaction catalysed:
Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.
Systematic name:
Adenine-DNA deoxyribohydrolase (adenine-releasing)
Alternative Name(s):
- A/G-specific adenine glycosylase
- MutY (gene name)
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence families
Protein families (Pfam)
InterPro annotations
Structure domains
CATH domains
1.10.1670.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
Endonuclease Iii, domain 2
Homology:
Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)
Occurring in: