Function and Biology Details
Reaction catalysed:
Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123527 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
CurD
Molecule details ›
Chain: A
Length: 443 amino acids
Theoretical weight: 49.24 KDa
Source organism: Moorena producens 3L
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 443 amino acids
Theoretical weight: 49.24 KDa
Source organism: Moorena producens 3L
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
F4Y432 (Residues: 1-419; Coverage: 100%)
Sequence domains:
- Hydroxymethylglutaryl-coenzyme A synthase N terminal
- Hydroxymethylglutaryl-coenzyme A synthase C terminal
Carrier domain-containing protein
Molecule details ›
Chain: B
Length: 103 amino acids
Theoretical weight: 11.57 KDa
Source organism: Lyngbya majuscula
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Phosphopantetheine attachment site
Structure domains: ACP-like
Length: 103 amino acids
Theoretical weight: 11.57 KDa
Source organism: Lyngbya majuscula
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q6DNF1 (Residues: 1-79; Coverage: 100%)
Sequence domains: Phosphopantetheine attachment site
Structure domains: ACP-like
