› 5lgj

X-ray diffraction
2.6Å resolution

THE CRYSTAL STRUCTURE OF IGE FC MUTANT - P333C

Released:
DOI: 10.2210/pdb5lgj/pdb
PDB entry 5lgj coloured by chain, front view.
PDB entry 5lgj coloured by chain, side view.
PDB entry 5lgj coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Dhaliwal B, Pang MOY, Sutton BJ

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134790 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Immunoglobulin heavy constant epsilon Chain: A
Molecule details ›
Chain: A
Length: 319 amino acids
Theoretical weight: 35.53 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
  • Canonical: P01854 (Residues: 108-426; Coverage: 58%)
Gene name: IGHE
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Immunoglobulin heavy constant epsilon Chain: B
Molecule details ›
Chain: B
Length: 320 amino acids
Theoretical weight: 35.59 KDa
Source organism: Homo sapiens
Expression system: Mus musculus
UniProt:
  • Canonical: P01854 (Residues: 108-427; Coverage: 59%)
Gene name: IGHE
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
3 bound ligands:
Ligand SO4 4 x SO4
Ligand PG4 2 x PG4
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21212
Unit cell:
a: 129.45Å b: 74.91Å c: 79.06Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.188 0.248
Expression system: Mus musculus

Quick links